Scientific Name: Felis catus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Carnivora-> Feliformia-> Felidae
Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_0028 | 2021.04 | 10X Genomics | Esophagus | Normal | 1928 | Link |
| Vthunter_0029 | 2021.04 | 10X Genomics | Eyelid | Normal | 679 | Link |
| Vthunter_0030 | 2021.04 | 10X Genomics | Heart | Normal | 8209 | Link |
| Vthunter_0031 | 2021.04 | 10X Genomics | Kidney | Normal | 2831 | Link |
| Vthunter_0032 | 2021.04 | 10X Genomics | Liver | Normal | 7889 | Link |
| Vthunter_0033 | 2021.04 | 10X Genomics | Lung | Normal | 8591 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in fat (RPKM 188.8), lung (RPKM 142.9) and 25 other tissues?
